Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833336 | 0.85 | ITGB3 (0.45) | P2RX3KMT2ASMN1; SMN2ESR2MAPT | |
| SCHEMBL8557342 | 0.83 | P2RX3 (0.40) | P2RX3KMT2AMEN1ALDH1A1BRD4 | |
| SCHEMBL8558144 | 0.75 | ITGB3 (0.45) | P2RX3ESR2NR1H2MAPT | |
| SCHEMBL7834582 | 0.75 | ITGB3 (0.47) | KMT2AMEN1SMN1; SMN2BRD4CREBBP | |
| SCHEMBL8553064 | 0.75 | ITGB3 (0.62) | SMN1; SMN2HTT | |
| SCHEMBL5548036 | 0.75 | ESR2 (0.48) | P2RX3BRD4CREBBPESR2NR1H2 | |
| SCHEMBL7992597 | 0.74 | ESR2 (0.50) | P2RX3SMN1; SMN2BRD4CREBBPESR2 | |
| Trifluoroacetic Acid SCHEMBL8554545 | 0.74 | ITGB3 (0.50) | KMT2AMEN1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL8560838 | 0.74 | PRMT5 (0.46) | — | |
| SCHEMBL8833267 | 0.73 | ITGB3 (0.48) | KMT2AMEN1SMN1; SMN2BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |