Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833774 | 0.95 | FDPS (0.35) | SMN1; SMN2MAPK10FDPSCCNE1CDK2 | |
| SCHEMBL8834125 | 0.91 | FDPS (0.37) | SMN1; SMN2MAPK10FDPSCCNE1CDK2 | |
| SCHEMBL8832893 | 0.90 | FDPS (0.39) | SMN1; SMN2MAPK10FDPSCCNE1CDK2 | |
| SCHEMBL8833145 | 0.85 | CDK2 (0.38) | SMN1; SMN2MAPK10FDPSCCNE1CDK2 | |
| SCHEMBL8833431 | 0.84 | CCNE1 (0.41) | SMN1; SMN2FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833079 | 0.79 | FDPS (0.40) | SMN1; SMN2FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833251 | 0.78 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPK10CCNE1CDK2CDK5 | |
| SCHEMBL8833783 | 0.75 | FDPS (0.41) | SMN1; SMN2FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833522 | 0.74 | NAAA (0.33) | SMN1; SMN2MAPK10CCNE1CDK2CDK5 | |
| SCHEMBL8833680 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2FDPSCCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |