Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418459 | 0.79 | KDM4E (0.56) | MEN1KMT2AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL2223207 | 0.77 | AR (0.48) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL28978243 | 0.77 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL28129138 | 0.77 | RAB9A (0.56) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL5106250 | 0.72 | RAB9A (0.62) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL5888794 | 0.72 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL43510 | 0.72 | KDM4E (0.60) | MEN1KMT2AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL29506855 | 0.72 | KDM4E (0.60) | MEN1KMT2AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL929603 | 0.72 | ALDH1A1 (0.60) | MEN1KMT2AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL11363544 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2AKDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9188665-A | — | — | None | — | — | JP | disclosed |
| JP-H09188665-A | NEW SUBSTITUTED N-QUINOLYLANTHRANYL ACID REDIVATIVE AND PRODUCTION OF THE SAME | KYORIN PHARMACEUT CO LTD | 1997-07-22 | — | — | JP | disclosed |