Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 2/20 | 0.61 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 15/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834803 | 0.94 | AGER (0.59) | AGERPPARAARMAOBKDM4E | |
| SCHEMBL8835233 | 0.91 | AGER (0.62) | AGERPPARAARMAOB | |
| SCHEMBL7915805 | 0.87 | AGER (0.67) | AGERPPARAARMAOB | |
| SCHEMBL8835405 | 0.85 | AR (0.54) | AGERPPARAARMAOBKDM4E | |
| SCHEMBL8835021 | 0.85 | KMT2A (0.60) | ARMAOBKDM4EMEN1ALDH1A1 | |
| SCHEMBL8834871 | 0.82 | KDM4E (0.59) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7914253 | 0.82 | AGER (0.62) | AGERPPARAARMAOB | |
| SCHEMBL4579567 | 0.81 | AR (0.69) | AGERPPARAARMAOB | |
| SCHEMBL8835114 | 0.80 | ALDH1A1 (0.65) | MAOBKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8834965 | 0.80 | MAOB (0.58) | ARMAOBKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | claimed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | claimed |
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |