Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | HPGD | P15428 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835021 | 0.86 | KMT2A (0.60) | KDM4EALDH1A1HPGDKMT2ATDP1 | |
| SCHEMBL8834943 | 0.82 | AGER (0.61) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7907510 | 0.82 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL8835114 | 0.81 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL11946745 | 0.81 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL8835418 | 0.81 | MAOB (0.60) | KDM4EALDH1A1HPGDKMT2ATDP1 | |
| SCHEMBL8834965 | 0.81 | MAOB (0.58) | KDM4EALDH1A1HPGDKMT2ATDP1 | |
| SCHEMBL8835331 | 0.80 | CA12 (0.60) | KDM4EALDH1A1HPGDTDP1POLB | |
| SCHEMBL11946746 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDKMT2APKM | |
| SCHEMBL13779255 | 0.78 | KDM4E (0.73) | KDM4EALDH1A1HPGDKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |