SCHEMBL8834978

SCHEMBL8834978

C=CC(=O)Oc1ccc([C@H]2CC[C@H](CCCC)CC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.52
CYP2C9 P11712 1/20 0.48
MAPT P10636 2/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
RAB9A P51151 1/20 0.43
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
THRA P10827 1/20 0.40
ESR2 Q92731 3/20 0.38
LSS P48449 1/20 0.38
NAAA Q02083 1/20 0.36
SPHK1 Q9NYA1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75087 1.00 THRB (0.52) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL76060 0.96 THRB (0.49) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL816087 0.96 THRB (0.54) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL12386501 0.93 THRB (0.51) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL74879 0.92 CYP2C9 (0.57) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL1655552 0.92 CYP2C9 (0.57) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL14373521 0.90 THRB (0.48) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL74271 0.89 CYP2C9 (0.53) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL12386500 0.89 CYP2C9 (0.53) THRBCYP2C9MAPTALDH1A1LMNA
SCHEMBL14010374 0.88 RAB9A (0.45) THRBCYP2C9MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9316032-A None JP disclosed
JP-H09316032-A ACRYLATE COMPOUND AND LIQUID CRYSTAL DEVICE PRODUCED BY USING THE COMPOUND DAINIPPON INK & CHEM INC 1997-12-09 JP disclosed