Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834978 | 0.96 | THRB (0.52) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL75087 | 0.96 | THRB (0.52) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL816087 | 0.93 | THRB (0.54) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL74271 | 0.93 | CYP2C9 (0.53) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL12386501 | 0.89 | THRB (0.51) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL74879 | 0.89 | CYP2C9 (0.57) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL1655552 | 0.89 | CYP2C9 (0.57) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL14088485 | 0.89 | RAB9A (0.42) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL14373521 | 0.86 | THRB (0.48) | THRBCYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL14088483 | 0.85 | RAB9A (0.42) | THRBCYP2C9MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992796-B2 | Polymerizable liquid crystal composition | DIC CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8992796-B2 | Polymerizable liquid crystal composition | DIC CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8168734-B2 | Lateral alpha-substituted acrylate compound and polymer thereof | JNC CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168734-B2 | Lateral alpha-substituted acrylate compound and polymer thereof | JNC CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8139189-B2 | Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal | DAI NIPPON PRINTING CO., LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20120056129-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |
| US-8130358-B2 | Liquid crystal display | DAI NIPPON PRINTING CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-8094269-B2 | Liquid crystal display device, manufacturing method thereof, and color filter substrate | HITACHI DISPLAYS, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-8009266-B2 | Process for producing liquid crystal display | DAI NIPPON PRINTING CO., LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| US-20110144293-A1 | LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF | CHISSO CORPORATION (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-20080074588-A1 | LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF | MAGNOLIA PURPLE CORPORATION (JP) | 2008-03-27 | — | — | US | disclosed |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | CHISSO CORPORATION | 2007-06-14 | — | — | US | disclosed |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | CHISSO CORPORATION | 2007-06-14 | — | — | US | disclosed |
| US-20070026165-A1 | Liquid crystal display and manufacturing method of same | DAI NIPPON PRINTING CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| US-20070026165-A1 | Liquid crystal display and manufacturing method of same | DAI NIPPON PRINTING CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| US-7157124-B2 | Polymerizable compounds and their polymers | CHISSO PETROCHEMICAL CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157124-B2 | Polymerizable compounds and their polymers | CHISSO PETROCHEMICAL CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144293-A1 | LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF | LEF1, AFF1, CNKSR1 | THRB 1814/4885CYP2C9 4548/4885MAPT 3921/4885 |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | AFF1, CNKSR1, LEF1 | THRB 3134/4885CYP2C9 4328/4885MAPT 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.