Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835351 | 0.96 | L3MBTL1 (0.36) | L3MBTL1GRM2KDM1AESR2RCOR1 | |
| SCHEMBL8835310 | 0.93 | L3MBTL1 (0.34) | L3MBTL1GRM2KDM1AESR2RCOR1 | |
| SCHEMBL8835312 | 0.89 | L3MBTL1 (0.40) | L3MBTL1MMP12CHRM2CHRM1P2RY14 | |
| SCHEMBL8835171 | 0.85 | DGAT1 (0.31) | CHRM2CHRM1ESR2CHRM5CHRM3 | |
| SCHEMBL8835178 | 0.85 | KDM1A (0.39) | L3MBTL1GRM2KDM1AESR2RCOR1 | |
| SCHEMBL8835143 | 0.85 | CTSK (0.36) | CHRM2CHRM1GRM2EPHX2CHRM5 | |
| SCHEMBL8835268 | 0.84 | HTR2C (0.42) | CHRM2CHRM1P2RY14GRM2ESR2 | |
| SCHEMBL8835096 | 0.84 | ESR2 (0.37) | ESR2CYP2C9 | |
| SCHEMBL8835121 | 0.81 | CYP2C9 (0.39) | ESR2CYP2C9 | |
| SCHEMBL6141770 | 0.81 | L3MBTL1 (0.38) | L3MBTL1MMP12CHRM2CHRM1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |