Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.58 |
| ▸ | TSHR | P16473 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308638 | 0.91 | HSD17B10 (0.75) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL11314567 | 0.89 | HSD17B10 (0.73) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL68786 | 0.84 | HSD17B10 (0.82) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| Water SCHEMBL8652184 | 0.80 | HPGD (0.75) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL21409526 | 0.80 | HSD17B10 (0.75) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL3468538 | 0.80 | HSD17B10 (0.75) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL6437397 | 0.80 | HSD17B10 (0.91) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| Tetrachlorohydroquinone SCHEMBL48198 | 0.78 | HSD17B10 (0.90) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| SCHEMBL3308498 | 0.75 | TSHR (0.44) | HSD17B10TSHRHPGDALDH1A1MEN1 | |
| Pentachlorophenol SCHEMBL23121452 | 0.74 | HSD17B10 (1.00) | HSD17B10TSHRHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606010-A | REACTING A DIAMINE AND A QUINONE COMPOUND IN PRESENCE OF AN OXIDIZER | Erhan, Semih (US) | 1997-02-25 | — | — | US | claimed |