SCHEMBL8835969

SCHEMBL8835969

CC(C)(C)CC(C)(C)c1cc(Br)[c]c(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.42
CYP3A4 P08684 4/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HIF1A Q16665 2/20 0.34
IDH1 O75874 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP2D6 P10635 1/20 0.33
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
ESR1 P03372 1/20 0.30
TP53 P04637 1/20 0.30
PGR P06401 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
AR P10275 1/20 0.30
MAPT P10636 1/20 0.30
DRD1 P21728 1/20 0.30
PTGS1 P23219 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11299088 0.76 SHBG (0.43) SHBGCYP3A4SMN1; SMN2HIF1AIDH1
SCHEMBL20339731 0.76 SHBG (0.43) SHBGCYP3A4SMN1; SMN2HIF1AIDH1
SCHEMBL8961124 0.74 SHBG (0.42) SHBGCYP3A4SMN1; SMN2HIF1AIDH1
SCHEMBL8836407 0.74 SHBG (0.42) SHBGCYP3A4SMN1; SMN2HIF1AIDH1
SCHEMBL7556002 0.74 ALOX15 (0.48) CYP3A4HIF1AALDH1A1ALOX15HSD17B10
SCHEMBL8836707 0.74 GABRA1 (0.42) CYP3A4HIF1AALDH1A1CYP2C9ALOX15
SCHEMBL200255 0.71 SHBG (0.43) SHBGCYP3A4SMN1; SMN2HIF1AIDH1
SCHEMBL15067863 0.71 SHBG (0.39) SHBGCYP3A4SMN1; SMN2HIF1AIDH1
SCHEMBL5054603 0.69 SHBG (0.38) SHBGCYP3A4SMN1; SMN2HIF1AIDH1
SCHEMBL15067135 0.69 SHBG (0.38) SHBGCYP3A4SMN1; SMN2HIF1AIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639900-A MOLYBDENUM OR TUGSTEN COMPLEXES METTON AMERICA, INC. (US) 1997-06-17 US disclosed
US-5606085-A PHYSICAL ACTIVATION OF TRANSITIONAL BASED COMPLEX METTON AMERICA, INC. (US) 1997-02-25 US disclosed