Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABAT | P80404 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.31 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA2 | P00918 | 4/20 | 0.31 |
| ▸ | CA9 | Q16790 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835864 | 0.82 | ALDH1A1 (0.34) | NLRP3ALDH1A1LMNAHSD17B10ABAT | |
| SCHEMBL8333602 | 0.79 | NLRP3 (0.39) | NLRP3ALDH1A1LMNAHSD17B10 | |
| SCHEMBL17029137 | 0.78 | NLRP3 (0.43) | NLRP3ALDH1A1LMNAHSD17B10CA12 | |
| SCHEMBL13031121 | 0.78 | NLRP3 (0.38) | NLRP3ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8447099 | 0.77 | NLRP3 (0.36) | NLRP3LMNA | |
| SCHEMBL8472969 | 0.77 | NLRP3 (0.36) | NLRP3LMNA | |
| SCHEMBL8472968 | 0.77 | NLRP3 (0.36) | NLRP3LMNA | |
| SCHEMBL1738333 | 0.76 | NLRP3 (0.37) | NLRP3ALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL1738334 | 0.76 | NLRP3 (0.37) | NLRP3ALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL5485344 | 0.76 | NLRP3 (0.37) | NLRP3ALDH1A1HSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688933-A | Preparation of biologically active compounds from substantially pure enantiomers of 2-azabicyclo 2.2.1!hept-5-en-one | CHIROSCIENCE, LTD. (GB) | 1997-11-18 | — | — | US | claimed |