Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | AHR | P35869 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809358 | 0.94 | AHR (0.55) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL2628334 | 0.94 | AHR (0.59) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL30743074 | 0.94 | AHR (0.59) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL883669 | 0.92 | MAOA (0.60) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL15785771 | 0.86 | MAPT (0.55) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL808014 | 0.86 | MAPT (0.59) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL1635601 | 0.85 | AHR (0.68) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL13564024 | 0.85 | DYRK1A (0.49) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL17899746 | 0.84 | AHR (0.52) | MAOAAHRMEN1KMT2AMAPT | |
| SCHEMBL10141873 | 0.84 | MAOB (0.47) | AHRMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-11917913-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2024-02-27 | — | — | US | disclosed |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | MERCK PATENT GMBH (DE) | 2019-09-12 | — | — | US | disclosed |
| US-10374170-B2 | Substituted oxepines | MERCK PATENT GMBH (DE) | 2019-08-06 | — | — | US | disclosed |
| EP-2673249-B1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2651862-B1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| US-9598637-B2 | Phosphorus-containing metal complexes | MERCK PATENT GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| EP-3121183-A1 | METALS CONTAINING ORGANIC COMPLEXES | Merck Patent GmbH (DE) | 2017-01-25 | — | — | EP | disclosed |
| EP-2896627-B1 | Metals containing organic complexes | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130261708-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012107163-A1 | SUBSTITUTED DIBENZONAPHTHACENE | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012079678-A1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012038029-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012007103-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11917913-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | MAOA 161/4885AHR 1161/4885MEN1 2568/4885 |
| US-10374170-B2 | Substituted oxepines | OXGR1, OXTR, OCIAD2 | MAOA 161/4885AHR 1161/4885MEN1 2568/4885 |
| US-20190280218-A1 | SUBSTITUTED OXEPINES | OXGR1, OXTR, OCIAD2 | MAOA 161/4885AHR 1161/4885MEN1 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.