SCHEMBL8837199

SCHEMBL8837199

CSc1ccc(OCc2ccccc2)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
MAOA P21397 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ALOX5 P09917 1/20 0.51
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
CYP2C19 P33261 1/20 0.46
PTGS2 P35354 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HIF1A Q16665 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
CYP3A4 P08684 1/20 0.46
NOS3 P29474 1/20 0.45
NOS1 P29475 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684901 0.83 ALOX5 (0.53) MAOBGAAMAPTMAOARAB9A
SCHEMBL9049716 0.83 MAOB (0.57) MAOBGAAMAPTMAOARAB9A
SCHEMBL11957592 0.80 MAPT (0.46) MAOBGAAMAPTMAOARAB9A
SCHEMBL3119532 0.80 MAOB (0.55) MAOBGAAMAPTMAOARAB9A
SCHEMBL30040891 0.80 MAOB (0.63) MAOBGAAMAPTMAOARAB9A
SCHEMBL4473165 0.80 MAOB (0.63) MAOBGAAMAPTMAOARAB9A
SCHEMBL1734928 0.79 LMNA (0.59) MAOBGAAMAPTMAOARAB9A
SCHEMBL2852071 0.79 MAOB (0.58) MAOBGAAMAPTMAOARAB9A
SCHEMBL811334 0.79 CYP1A2 (0.55) MAOBGAAMAPTMAOARAB9A
Hydrochloric Acid SCHEMBL9124176 0.78 MAOB (0.61) MAOBGAAMAPTMAOARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5616809-A COUPLER, USED TO DYE KERATINOUS FIBERS L'OREAL (FR) 1997-04-01 US disclosed
EP-0591060-B1 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation OREAL (FR) 1996-12-18 EP disclosed
US-5451236-A Hair dyes L'OREAL (FR) 1995-09-19 US disclosed
EP-0591060-A1 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation L'OREAL (FR) 1994-04-06 EP disclosed