SCHEMBL8837367

SCHEMBL8837367

CC(C)C[CH]C(=O)CC(N)=O

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.36
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491235 0.75
SCHEMBL131167 0.73
SCHEMBL8218773 0.71
SCHEMBL129081 0.70 CES2 (0.38) GRIK1
SCHEMBL29052605 0.70
SCHEMBL127452 0.67
SCHEMBL125682 0.67
SCHEMBL491289 0.67
SCHEMBL125807 0.67
SCHEMBL8837390 0.67 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5194415-A None JP disclosed
US-5643908-A ANGIOGENESIS INHIBITOR, ANTITUMOR SANKYO COMPANY, LIMITED (JP) 1997-07-01 US disclosed
EP-0621270-A1 COLLAGENASE INHIBITOR SANKYO COMPANY LIMITED (JP) 1994-10-26 EP disclosed
JP-H05194415-A COLLAGENASE INHIBITOR SANKYO CO LTD 1993-08-03 JP disclosed