Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266767 | 1.00 | KDM4E (0.57) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL23493263 | 0.92 | KDM4E (0.64) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL30184764 | 0.92 | KDM4E (0.64) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL23493265 | 0.92 | KDM4E (0.64) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL8668852 | 0.87 | KDM4E (0.59) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL3387910 | 0.87 | KDM4E (0.59) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL6557860 | 0.85 | MAPT (0.58) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL12890771 | 0.85 | KLK5 (0.51) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL30471370 | 0.85 | KLK5 (0.51) | KDM4EHPGDGLAGAAMAPT | |
| SCHEMBL4320299 | 0.85 | KDM4E (0.67) | KDM4EHPGDGLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695271-A2 | A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA | Merck Sharp & Dohme LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024215820-A2 | A CYCLIC PEPTIDE FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2024-10-17 | — | — | WO | disclosed |
| EP-4108648-A1 | METHOD FOR PRODUCING AROMATIC ASTATINE COMPOUND | National University Corporation Hokkaido University (JP) | 2022-12-28 | — | — | EP | disclosed |
| US-20220356205-A1 | METHOD FOR PRODUCING AROMATIC ASTATINE COMPOUND | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2022-11-10 | — | — | US | disclosed |
| WO-2021149814-A1 | CATALYST FOR MANUFACTURING AMIDE COMPOUND, AND METHOD FOR MANUFACTURING AMIDE COMPOUND | 学校法人中部大学 | 2021-07-29 | — | — | WO | disclosed |
| US-5674864-A | ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356205-A1 | METHOD FOR PRODUCING AROMATIC ASTATINE COMPOUND | AANAT, AADAT, ALK | KDM4E 3008/4885HPGD 4318/4885GLA 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.