Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511512 | 1.00 | KDM4E (0.67) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL28536811 | 1.00 | KDM4E (0.67) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL23493263 | 0.86 | KDM4E (0.64) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL23493265 | 0.86 | KDM4E (0.64) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL30184764 | 0.86 | KDM4E (0.64) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL8837503 | 0.85 | KDM4E (0.57) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL7266767 | 0.85 | KDM4E (0.57) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL17906528 | 0.82 | KDM4E (0.48) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL7901353 | 0.82 | RECQL (0.56) | KDM4EHPGDMAPTGAAGLA | |
| SCHEMBL11418968 | 0.81 | CTSS (0.60) | KDM4EHPGDEPHX2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512529-B | Cyclopentenepurine derivative or salt thereof | 富士胶片株式会社 | 2024-06-18 | — | — | CN | disclosed |
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2023-09-21 | — | — | US | disclosed |
| US-20210155644-A1 | CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2021-05-27 | — | — | US | disclosed |
| US-20210147456-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2021-05-20 | — | — | US | disclosed |
| CN-112512529-A | Cyclopentene purine derivatives or salts thereof | 富士胶片株式会社 | 2021-03-16 | — | — | CN | disclosed |
| US-9133262-B2 | Somatostatin antagonists | IPSEN PHARMA S.A.S. (FR) | 2015-09-15 | — | — | US | disclosed |
| US-20090253638-A1 | Somatostatin Antagonists | BIOMEASURE, INCORPORATED | 2009-10-08 | — | — | US | disclosed |
| US-7550423-B2 | Somatostatin antagonists | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2009-06-23 | — | — | US | disclosed |
| US-20040097418-A1 | Somatostatin antagonists | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. | 2004-05-20 | — | — | US | disclosed |
| US-6703481-B1 | USE OF PEPTIDES INCORPORATING D-AMINO ACID TO PROMOTE THE RELEASE OF GROWTH HORMONE OR INSULIN, ENHANCING WOUND HEALING OR PROMOTING ANGIOGENESIS | THE ADMINISTRATION OF THE TULANE EDUCATIONAL FUND | 2004-03-09 | — | — | US | disclosed |
| US-6262229-B1 | OCTAPEPTIDES | BIOMEASURE INCORPORATED | 2001-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | SLC28A1, SLC20A1, SLC29A1 | KDM4E 4331/4885HPGD 1367/4885MAPT 4397/4885 |
| US-20210147456-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | SLC28A1, SLC20A1, SLC29A1 | KDM4E 4331/4885HPGD 1367/4885MAPT 4397/4885 |
| US-20090253638-A1 | Somatostatin Antagonists | SSTR5, SSTR2, SSTR4 | KDM4E 2789/4885HPGD 4342/4885MAPT 4560/4885 |
| US-20210155644-A1 | CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF | SLC28A1, SLC20A1, NOX1 | KDM4E 4014/4885HPGD 756/4885MAPT 4166/4885 |
| US-20040097418-A1 | Somatostatin antagonists | SSTR5, SSTR2, SSTR4 | KDM4E 2789/4885HPGD 4342/4885MAPT 4560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.