Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 3/20 | 0.60 |
| ▸ | MME | P08473 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588091 | 0.87 | MME (0.62) | CTRB1MME | |
| SCHEMBL8837483 | 0.86 | CTRB1 (0.73) | CTRB1MME | |
| SCHEMBL7299958 | 0.84 | MME (0.66) | CTRB1MMEKMT2AMEN1 | |
| SCHEMBL9587974 | 0.83 | KMT2A (0.54) | KMT2AMEN1TSHROPRM1EPHX1 | |
| SCHEMBL9588438 | 0.81 | LMNA (0.60) | CTRB1MMETSHR | |
| SCHEMBL7304189 | 0.80 | CTRB1 (0.65) | CTRB1MME | |
| SCHEMBL9587977 | 0.80 | KMT2A (0.59) | MMEKMT2AMEN1TSHROPRM1 | |
| SCHEMBL8837460 | 0.79 | MME (0.73) | CTRB1MME | |
| SCHEMBL9852784 | 0.78 | KMT2A (0.60) | KMT2AMEN1TSHREPHX1ANPEP | |
| SCHEMBL9587929 | 0.78 | KMT2A (0.51) | CTRB1MMEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674864-A | ANALGESICS; ENDOPEPTIDASE AND ENKEPHALINASE INHIBITORS; CARDIOTONIC, PSYCHOTROPIC AND HYPERTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1997-10-07 | — | — | US | disclosed |
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |