Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354738 | 1.00 | MEN1 (0.60) | MEN1KMT2AALDH1A1MAPTAPEX1 | |
| SCHEMBL3103301 | 0.85 | MEN1 (0.81) | MEN1KMT2AALDH1A1MAPTAPEX1 | |
| SCHEMBL8837588 | 0.81 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPTAPEX1 | |
| SCHEMBL11982925 | 0.81 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTAPEX1 | |
| SCHEMBL8837552 | 0.73 | LMNA (0.61) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL852717 | 0.72 | AKR1C2 (0.76) | MEN1KMT2AALDH1A1MAPTAPEX1 | |
| SCHEMBL8229566 | 0.72 | MAPT (0.87) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL4463990 | 0.72 | PLA2G4A (0.49) | MEN1KMT2AALDH1A1MAPTAPEX1 | |
| SCHEMBL7908389 | 0.69 | MAPT (0.53) | MEN1KMT2AALDH1A1MAPTAPEX1 | |
| SCHEMBL8272455 | 0.68 | MAPT (0.72) | MEN1KMT2AALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113968809-A | Chemical synthesis method of melatonin | 太阳树(莆田)生物医药有限公司 | 2022-01-25 | — | — | CN | claimed |
| US-RE35631-E | Method of production of essentially pure melatonin and the method of solubilizing melatonin in water | IFLO S.A.S. (IT) | 1997-10-14 | — | — | US | claimed |
| EP-0330625-B1 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I F L O S A S DI GIORGIO E ALD (IT) | 1995-12-20 | — | — | EP | claimed |
| EP-0330625-A2 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi (IT) | 1989-08-30 | — | — | EP | claimed |
| CN-113968809-A | Chemical synthesis method of melatonin | 太阳树(莆田)生物医药有限公司 | 2022-01-25 | — | — | CN | disclosed |
| US-RE35631-E | Method of production of essentially pure melatonin and the method of solubilizing melatonin in water | IFLO S.A.S. (IT) | 1997-10-14 | — | — | US | disclosed |
| US-RE35631-E | Method of production of essentially pure melatonin and the method of solubilizing melatonin in water | IFLO S.A.S. (IT) | 1997-10-14 | — | — | US | disclosed |
| EP-0330625-B1 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I F L O S A S DI GIORGIO E ALD (IT) | 1995-12-20 | — | — | EP | disclosed |
| US-5122535-A | Mixing with adenosine; treating AIDS | IFLO S.A.S. (IT) | 1992-06-16 | — | — | US | disclosed |
| US-5122535-A | Mixing with adenosine; treating AIDS | IFLO S.A.S. (IT) | 1992-06-16 | — | — | US | disclosed |
| EP-0330625-A3 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi (IT) | 1991-09-18 | — | — | EP | disclosed |
| EP-0330625-A2 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi (IT) | 1989-08-30 | — | — | EP | disclosed |
| EP-0330625-A2 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi (IT) | 1989-08-30 | — | — | EP | disclosed |