Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12758951 | 0.82 | HRH3 (0.56) | LMNAHPGDALDH1A1NPSR1RXFP1 | |
| SCHEMBL4470856 | 0.81 | MAPT (0.52) | LMNAHPGDALDH1A1NPSR1RXFP1 | |
| SCHEMBL11354778 | 0.77 | GPR84 (0.44) | LMNAHPGDALDH1A1NPSR1RXFP1 | |
| SCHEMBL11982925 | 0.75 | MEN1 (0.58) | LMNAHPGDALDH1A1NPSR1RXFP1 | |
| SCHEMBL867547 | 0.75 | LOXL2 (0.75) | LMNAHPGDALDH1A1HRH3MAPT | |
| SCHEMBL8229566 | 0.75 | MAPT (0.87) | LMNAHPGDALDH1A1NPSR1RXFP1 | |
| SCHEMBL6995767 | 0.74 | AHR (0.67) | HPGDALDH1A1HRH3MAPTMEN1 | |
| SCHEMBL7952644 | 0.74 | LOXL2 (0.69) | LMNAHPGDALDH1A1HRH3MAPT | |
| SCHEMBL8801068 | 0.74 | GPR84 (0.51) | LMNAHPGDALDH1A1NPSR1MAPT | |
| Hydrochloric Acid SCHEMBL9461291 | 0.74 | RAB9A (0.54) | LMNAHPGDALDH1A1NPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35631-E | Method of production of essentially pure melatonin and the method of solubilizing melatonin in water | IFLO S.A.S. (IT) | 1997-10-14 | — | — | US | disclosed |
| US-5122535-A | Mixing with adenosine; treating AIDS | IFLO S.A.S. (IT) | 1992-06-16 | — | — | US | disclosed |
| EP-0330625-A2 | Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes | I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi (IT) | 1989-08-30 | — | — | EP | disclosed |