SCHEMBL8837566

SCHEMBL8837566

O=C(OC1CCS1)c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 4/20 0.35
TSHR P16473 3/20 0.35
KDM4E B2RXH2 3/20 0.35
PTPN2 P17706 2/20 0.35
PTPN1 P18031 2/20 0.35
PTPRF P10586 1/20 0.35
POLB P06746 1/20 0.35
SCN1A P35498 3/20 0.32
SCN2A Q99250 3/20 0.32
SCN3A Q9NY46 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR3A P46098 1/20 0.31
ACLY P53396 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8837655 0.86 CA1 (0.55) CA1CA2CA5ACA9ALDH1A1
SCHEMBL9706642 0.81 L3MBTL1 (0.39) ALDH1A1HSD17B10TSHRKDM4EPTPN2
SCHEMBL8837628 0.78 ALDH1A1 (0.60) CA1CA2CA5ACA9ALDH1A1
SCHEMBL8837565 0.75 PTPN2 (0.42) CA1CA2CA5ACA9ALDH1A1
SCHEMBL28670609 0.74 CA1 (0.49) CA1CA2CA5ACA9ALDH1A1
SCHEMBL28005990 0.73 CA1 (0.47) CA1CA2CA5ACA9ALDH1A1
SCHEMBL427915 0.72 CA1 (0.69) CA1CA2CA5ACA9ALDH1A1
SCHEMBL30545879 0.72 CA1 (0.69) CA1CA2CA5ACA9ALDH1A1
Benzene SCHEMBL27506311 0.70 CA1 (0.67) CA1CA2CA5ACA9ALDH1A1
SCHEMBL10499606 0.69 HSD17B10 (0.56) CA1CA2CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597779-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1997-01-28 US disclosed
US-5552368-A Sulfonylureas CIBA-GEIGY CORPORATION (US) 1996-09-03 US disclosed
US-5519148-A CHEMICAL INTERMEDIATES FOR HERBICIDES CIBA-GEIGY CORPORATION (US) 1996-05-21 US disclosed
US-5489695-A PREEMERGENCE, POSTEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1996-02-06 US disclosed
US-5412107-A Phenylsulfonylchloride intermediates useful for the preparation of herbicidally active sulfonylureas CIBA-GEIGY CORPORATION (US) 1995-05-02 US disclosed
US-5286709-A Sulfonylureas CIBA-GEIGY CORPORATION (US) 1994-02-15 US disclosed
US-5209771-A Herbicides CIBA-GEIGY CORPORATION (US) 1993-05-11 US disclosed