SCHEMBL8837565

SCHEMBL8837565

O=C(OC1COC1)c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 2/20 0.42
PTPN1 P18031 2/20 0.42
PTPRF P10586 1/20 0.42
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HTR3A P46098 7/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
SCN1A P35498 3/20 0.35
SCN2A Q99250 3/20 0.35
SCN3A Q9NY46 3/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8837627 0.85 CA1 (0.56) PTPN2PTPN1PTPRFALDH1A1KDM4E
SCHEMBL8837628 0.82 ALDH1A1 (0.60) PTPN2PTPN1PTPRFALDH1A1KDM4E
SCHEMBL9026170 0.80 SCN1A (0.40) PTPN2PTPN1PTPRFALDH1A1KDM4E
SCHEMBL8888943 0.80 PTPRF (0.38) PTPN2PTPN1PTPRFALDH1A1KDM4E
SCHEMBL9432844 0.78 PTPN2 (0.39) PTPN2PTPN1PTPRFALDH1A1KDM4E
SCHEMBL9025271 0.78 PTPRF (0.36) PTPN2PTPN1PTPRFALDH1A1KDM4E
SCHEMBL8837563 0.76 ALDH1A1 (0.39) PTPN2PTPN1PTPRFALDH1A1HSD17B10
SCHEMBL28670609 0.76 CA1 (0.49) ALDH1A1TSHRHSD17B10CA1CA2
SCHEMBL8837566 0.75 CA1 (0.38) PTPN2PTPN1PTPRFALDH1A1KDM4E
SCHEMBL9432855 0.74 MAPT (0.38) PTPN2PTPN1TSHRLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597779-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1997-01-28 US disclosed
US-5552368-A Sulfonylureas CIBA-GEIGY CORPORATION (US) 1996-09-03 US disclosed
US-5519148-A CHEMICAL INTERMEDIATES FOR HERBICIDES CIBA-GEIGY CORPORATION (US) 1996-05-21 US disclosed
US-5489695-A PREEMERGENCE, POSTEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1996-02-06 US disclosed
US-5412107-A Phenylsulfonylchloride intermediates useful for the preparation of herbicidally active sulfonylureas CIBA-GEIGY CORPORATION (US) 1995-05-02 US disclosed
US-5310722-A Synergistic composition comprising a sulfonylurea and a thiadiazolo[3,4-a]py CIBA-GEIGY CORPORATION (US) 1994-05-10 US disclosed
US-5286709-A Sulfonylureas CIBA-GEIGY CORPORATION (US) 1994-02-15 US disclosed
US-5209771-A Herbicides CIBA-GEIGY CORPORATION (US) 1993-05-11 US disclosed