SCHEMBL8837571

SCHEMBL8837571

CC(C)c1ccccc1C(O)=S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.50
GABRB2 P47870 2/20 0.50
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
LMNA P02545 2/20 0.46
GABRB1 P18505 2/20 0.46
TSHR P16473 2/20 0.46
FAAH O00519 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
HTR2B P41595 1/20 0.46
GABRA2 P47869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9419224 0.98 GABRA1 (0.48) GABRA1GABRB2GABRG2GABRB3LMNA
Thiobenzoic Acid SCHEMBL28412312 0.87 LMNA (0.40) GABRA1GABRB2GABRG2GABRB3LMNA
Thiobenzoic Acid SCHEMBL21633271 0.84 LMNA (0.38) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL28380709 0.80 GABRA1 (0.45) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL3103294 0.80 GABRA1 (0.52) GABRA1GABRB2GABRG2GABRB3LMNA
SCHEMBL8837659 0.79 GABRA1 (0.48) GABRA1GABRB2GABRG2GABRB3LMNA
Hydrogen Peroxide SCHEMBL99126 0.79 GABRA1 (0.65) GABRA1GABRB2GABRG2GABRB3LMNA
Hydrogen Peroxide SCHEMBL20593356 0.79 GABRA1 (0.65) GABRA1GABRB2GABRG2GABRB3LMNA
Hydrogen Peroxide SCHEMBL35519 0.79 GABRA1 (0.65) GABRA1GABRB2GABRG2GABRB3LMNA
Hydrogen Peroxide SCHEMBL30120583 0.79 GABRA1 (0.65) GABRA1GABRB2GABRG2GABRB3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476616-B Piperazinyl methanone NAAA inhibitors 加利福尼亚大学董事会 2023-10-13 CN disclosed
US-20120219885-A1 NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-08-30 US disclosed
CN-1039771-C Sulfonylureas compounds NOVATIS CO (CH) 1998-09-16 CN disclosed
US-5597779-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1997-01-28 US disclosed
US-5552368-A Sulfonylureas CIBA-GEIGY CORPORATION (US) 1996-09-03 US disclosed
US-5519148-A CHEMICAL INTERMEDIATES FOR HERBICIDES CIBA-GEIGY CORPORATION (US) 1996-05-21 US disclosed
US-5489695-A PREEMERGENCE, POSTEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1996-02-06 US disclosed
US-5412107-A Phenylsulfonylchloride intermediates useful for the preparation of herbicidally active sulfonylureas CIBA-GEIGY CORPORATION (US) 1995-05-02 US disclosed
EP-0626958-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1994-12-07 EP disclosed
US-5310722-A Synergistic composition comprising a sulfonylurea and a thiadiazolo[3,4-a]py CIBA-GEIGY CORPORATION (US) 1994-05-10 US disclosed
US-5286709-A Sulfonylureas CIBA-GEIGY CORPORATION (US) 1994-02-15 US disclosed
WO-1993017016-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1993-09-02 WO disclosed
US-5209771-A Herbicides CIBA-GEIGY CORPORATION (US) 1993-05-11 US disclosed
CN-1059446-A Synergism goods and the method for Selective Control weeds CIBA GEIGY AG (CH) 1992-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120219885-A1 NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF MEP1A, MMAB, RHOA GABRA1 3955/4885GABRB2 4640/4885GABRG2 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.