Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581203 | 0.91 | F2 (0.36) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7066093 | 0.70 | MEN1 (0.30) | — | |
| SCHEMBL7062105 | 0.70 | KMT2A (0.33) | F2PRSS1PRSS2PRSS3 | |
| Methylhydrazine SCHEMBL6952982 | 0.65 | — | — | |
| SCHEMBL9186647 | 0.61 | KDM4E (0.42) | F2PRSS1PRSS2PRSS3 | |
| Acetamide SCHEMBL28743112 | 0.61 | LMNA (0.50) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL585350 | 0.61 | CA1 (0.33) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28161482 | 0.61 | CA2 (0.35) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27770207 | 0.61 | F2 (0.33) | F2PRSS1PRSS2PRSS3 | |
| Urea SCHEMBL2959932 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637619-A | Antitumor 2-aminocarbonyl-1, 2-bis(methylsulfonyl)-1-(substituted)hydrazines | YALE UNIVERSITY (US) | 1997-06-10 | — | — | US | disclosed |