Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 4/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | KDM5C | P41229 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947098 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 | |
| SCHEMBL30276008 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 | |
| SCHEMBL5700562 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 | |
| SCHEMBL4947094 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 | |
| SCHEMBL621293 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 | |
| SCHEMBL803789 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 | |
| SCHEMBL31029421 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 | |
| SCHEMBL17819893 | 0.76 | FTO (0.67) | ALDH1A1KDM4EMAPTKDM5AKDM5C | |
| SCHEMBL8234963 | 0.76 | KDM4E (0.61) | ALDH1A1KDM4EMAPTL3MBTL1KDM5A | |
| SCHEMBL12015752 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTL3MBTL1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280142-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-15 | — | — | US | disclosed |
| US-9908852-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-06 | — | — | US | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072672-A1 | BIPYRIDYL COMPOUND | CBR1, NR0B2, ERBB2 | ALDH1A1 1501/4885KDM4E 3386/4885MAPT 4692/4885 |
| US-10280142-B2 | Bipyridyl compound | CBR1, NR0B2, ERBB2 | ALDH1A1 1501/4885KDM4E 3386/4885MAPT 4692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.