Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8838437 | 0.81 | PDE10A (0.55) | PDE10AHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL8838373 | 0.81 | PDE10A (0.51) | PDE10AHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL26964296 | 0.80 | PDE10A (0.54) | PDE10AHSP90AA1HSP90AB1MEN1KMT2A | |
| Bromide SCHEMBL8838451 | 0.80 | PDE10A (0.50) | PDE10AHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL27397063 | 0.79 | PDE10A (0.53) | PDE10AHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL10319610 | 0.78 | PDE10A (0.55) | PDE10AHSP90AA1HSP90AB1MEN1KMT2A | |
| SCHEMBL8838482 | 0.77 | PDE10A (0.44) | PDE10ALMNAPARP1KDM4ETDP1 | |
| SCHEMBL8099182 | 0.77 | PDE4A (0.40) | ALDH1A1PARP1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8811070 | 0.77 | HPGDS (0.56) | PDE10AMEN1KMT2ALMNAMAPT | |
| SCHEMBL7589324 | 0.77 | KDM4E (0.57) | PDE10AMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089758-C | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID CO (US) | 2002-08-28 | — | — | CN | disclosed |
| US-5625068-A | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| CN-1138035-A | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | CN | disclosed |
| EP-0747361-A1 | Substituted quinoline herbicide intermediates and process | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |