SCHEMBL88385

SCHEMBL88385

CC(C(=O)Oc1ccccc1)=C(CC1CO1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP1A2 P05177 1/20 0.35
PTGS2 P35354 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RAB9A P51151 1/20 0.35
MIF P14174 1/20 0.34
MGLL Q99685 2/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529078 0.85 TDP1 (0.41) ELANETDP1ALDH1A1RAB9AMIF
SCHEMBL28173118 0.85 TDP1 (0.42) ELANETDP1ALDH1A1RAB9AMIF
SCHEMBL28289437 0.83 HPGD (0.36) TDP1CYP1A2ALDH1A1RAB9AMGLL
SCHEMBL27668892 0.78 PTGS2 (0.49) ELANECYP1A2PTGS2
SCHEMBL529080 0.78 TDP1 (0.41) ELANETDP1ALDH1A1RAB9AMIF
SCHEMBL28038450 0.77 TDP1 (0.41) ELANETDP1ALDH1A1RAB9AMIF
SCHEMBL28053740 0.77 TDP1 (0.47) TDP1ALDH1A1MGLL
SCHEMBL7160074 0.76 TDP1 (0.42) TDP1ALDH1A1RAB9AMIFMGLL
SCHEMBL87436 0.76 ELANE (0.54) ELANETDP1CYP1A2ALDH1A1GAA
SCHEMBL4441964 0.76 TDP1 (0.45) ELANETDP1ALDH1A1RAB9AMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210252186-A1 AN ADHESIVE LAYERED MATRIX AND USES THEREOF NURAMI MEDICAL LTD. (IL) 2021-08-19 US claimed
EP-3802111-A1 AN ADHESIVE LAYERED MATRIX AND USES THEREOF Nurami Medical Ltd (IL) 2021-04-14 EP claimed
US-20120202171-A1 DENTAL APPLIANCE D ANJOU LISSA T (US) 2012-08-09 US claimed
US-20120093741-A1 DENTAL MASKING COMPOUND VOCO GMBH (DE) 2012-04-19 US claimed
US-8129188-B2 Cell culture apparatus and method of fabricating the apparatus INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-03-06 US claimed
US-20110250558-A1 DUAL-CURING, MULTI-COMPONENT DENTAL COMPOSITION VOCO GMBH (DE) 2011-10-13 US claimed
WO-2011106089-A1 BENZALKONIUM CHLORIDE COMPOSITIONS FOR INHIBITING THE HYDROLYTIC ACTIVITY OF ENDOGENOUS MATRIX METALLOPROTEINASES IN DENTAL RESTORATIONS BISCO, INC. (US) 2011-09-01 WO claimed
US-20110207844-A1 Benzalkonium chloride compositions for inhibiting the hydrolytic activity of endogenous matrix metalloproteinases in dental restorations BISCO, INC. 2011-08-25 US claimed
US-20110135749-A1 LOW SHRINKAGE MULTIFUNCTIONAL SSQ RESINS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-09 US claimed
WO-2009110848-A1 LOW SHRINKAGE MULTIFUNCTIONAL SSQ RESINS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-09-11 WO claimed
WO-2007024652-A2 DENTAL COMPOSITIONS BASED ON NANOFIBER REINFORCEMENT PREMIER DENTAL PRODUCTS COMPANY (US) 2007-03-01 WO claimed
US-20070043142-A1 DENTAL COMPOSITIONS BASED ON NANOFIBER REINFORCEMENT BJM LABORATORIES LTD. (IL) 2007-02-22 US claimed
US-6786720-B1 Epoxy resin bonding pad for a ceramic orthodontic appliance TP ORTHODONTICS, INC. 2004-09-07 US claimed
EP-1352617-A1 Epoxy resin bonding pad for a ceramic orthodontic appliance TP ORTHODONTICS, INC. (US) 2003-10-15 EP claimed
WO-2003013379-A2 DENTAL COMPOSITIONS B.J.M. LABORATORIES LTD. (IL) 2003-02-20 WO claimed
WO-2023083080-A1 TRANSPARENT EMBEDDING SOLVENT SYSTEM AND USE THEREOF CHINESE INSTITUTE FOR BRAIN RESEARCH, BEIJING (CN) 2023-05-19 WO disclosed
US-20210252186-A1 AN ADHESIVE LAYERED MATRIX AND USES THEREOF NURAMI MEDICAL LTD. (IL) 2021-08-19 US disclosed
US-6458869-B1 ETCHANT/PRIMER COMPOSITION, AN ETCHANT/PRIMER/ADHESIVE MONOMER COMPOSITION, KITS USING THE SAME AND METHODS USING THE SAME FOR IMPROVED BONDING TO DENTAL STRUCTURES. THE ETCHANT/PRIMER COMPOSITION COMPRISES A COMPOUND HAVING THE NATIONAL INSTITUTE OF STANDARDS OF TECHNOLOGY 2002-10-01 US disclosed
EP-0459361-A1 Dental filling band Din, Franklin M. (US) 1991-12-04 EP disclosed
US-5035615-A Dental filling band and method of use DIN FRANKLIN (US) 1991-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110135749-A1 LOW SHRINKAGE MULTIFUNCTIONAL SSQ RESINS SFPQ, PRDX1, SRSF1 ELANE 903/4885TDP1 2733/4885CYP1A2 3290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.