Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28173118 | 0.80 | TDP1 (0.42) | TDP1MGLLALDH1A1 | |
| SCHEMBL516278 | 0.79 | TDP1 (0.56) | TDP1MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL16241157 | 0.78 | ALDH1A1 (0.53) | TDP1MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL4838795 | 0.77 | ALDH1A1 (0.51) | TDP1MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL28018655 | 0.77 | TDP1 (0.46) | TDP1MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL88385 | 0.77 | ELANE (0.40) | TDP1MGLLALDH1A1 | |
| SCHEMBL2722563 | 0.75 | ALDH1A1 (0.55) | MGLLALDH1A1TP53CYP3A4 | |
| SCHEMBL17459253 | 0.75 | ALDH1A1 (0.59) | TDP1MGLLALDH1A1 | |
| SCHEMBL3429148 | 0.74 | MGLL (0.48) | TDP1MGLLALDH1A1 | |
| SCHEMBL88384 | 0.74 | ALDH1A1 (0.51) | TDP1MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105278242-A | Sensitive composition | TOKYO OHKA KOGYO CO LTD | 2016-01-27 | — | — | CN | disclosed |