Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840310 | 0.83 | KDM4E (0.54) | NPC1RAB9ARXFP1KDM4ESMN1; SMN2 | |
| SCHEMBL22617536 | 0.78 | KDM4E (0.42) | ALBNPC1RAB9ARXFP1KDM4E | |
| SCHEMBL22617533 | 0.76 | KDM4E (0.58) | NPC1RAB9APIM1KDM4ESMN1; SMN2 | |
| SCHEMBL8840161 | 0.74 | NPC1 (0.51) | NPC1RAB9AKDM4ESMN1; SMN2CA1 | |
| SCHEMBL8840334 | 0.74 | CSNK2A2 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8840148 | 0.72 | TTR (0.47) | TTRALBNPC1RAB9APIM1 | |
| SCHEMBL31341319 | 0.71 | HDAC6 (0.45) | TTRALBNPC1RAB9APIM1 | |
| SCHEMBL19814620 | 0.71 | TTR (0.46) | TTRALBPIM1KDM4ECA1 | |
| SCHEMBL8043690 | 0.71 | KDM4E (0.39) | NPC1RAB9APIM1PIM3RXFP1 | |
| SCHEMBL12571310 | 0.71 | TERT (0.43) | NPC1RAB9AKDM4ESMN1; SMN2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591695-A | Herbicidal [1,3,4]oxadiazoles and thiadiazoles | AMERICAN CYANAMID CO. (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0726263-A2 | Herbicidal (1,3,4)oxadiazoles and thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |