SCHEMBL8840314

SCHEMBL8840314

CC(COC(=O)[C@@H]1CCCN1)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.39
TLR2 O60603 2/20 0.39
DPP7 Q9UHL4 2/20 0.38
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
DPP4 P27487 1/20 0.34
FAP Q12884 1/20 0.34
DPP8 Q6V1X1 1/20 0.34
DPP9 Q86TI2 1/20 0.34
NOS2 P35228 2/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
KDM4E B2RXH2 1/20 0.33
IDO1 P14902 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263537 0.91 TLR2 (0.35) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL10363588 0.89 RAB9A (0.39) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL3714016 0.89 RAB9A (0.39) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL14887225 0.84 PRCP (0.44) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL5539757 0.84 RAB9A (0.38) PRCPTLR2CYP1A2CYP3A4CYP2D6
SCHEMBL24587253 0.84 TLR2 (0.40) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL27114716 0.84 TLR2 (0.40) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL19387299 0.84 PRCP (0.41) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL14887354 0.84 PRCP (0.44) PRCPTLR2DPP7CYP1A2CYP3A4
SCHEMBL14887236 0.84 PRCP (0.44) PRCPTLR2DPP7CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5616788-A FOR SOLID PHASE PEPTIDE SYNTHESIS HYUNDAI PHARM. IND. CO., LTD. (KR) 1997-04-01 US disclosed