Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27114716 | 1.00 | TLR2 (0.40) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL8840314 | 0.84 | PRCP (0.39) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL15323666 | 0.83 | TLR2 (0.36) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL24586243 | 0.83 | TLR2 (0.36) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL3714016 | 0.81 | RAB9A (0.39) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL10363588 | 0.81 | RAB9A (0.39) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL17732291 | 0.80 | PRCP (0.38) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL24586238 | 0.80 | DPP4 (0.36) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL25397085 | 0.79 | ADRB2 (0.36) | TLR2PRCPDPP7DPP4DPP8 | |
| SCHEMBL1263537 | 0.78 | TLR2 (0.35) | TLR2PRCPDPP7DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140458-A1 | PENETRATING CRYOPROTECTION AGENTS AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-06-30 | — | — | WO | disclosed |