Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 3/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840336 | 0.91 | NPC1 (0.52) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8840269 | 0.90 | TRPV1 (0.52) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8840339 | 0.90 | TDP1 (0.59) | NPC1RAB9AHPGDSMN1; SMN2TDP1 | |
| SCHEMBL8840201 | 0.89 | NPC1 (0.50) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8840271 | 0.84 | MEN1 (0.69) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11133448 | 0.83 | STK39 (0.55) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8840363 | 0.82 | MEN1 (0.62) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11359908 | 0.82 | NPC1 (0.66) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8658796 | 0.81 | PNLIP (0.62) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL11143585 | 0.81 | NPC1 (0.52) | NPC1RAB9AHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607977-A | PESTICIDES | SHELL AGRAR GMBH & CO. KG (DE) | 1997-03-04 | — | — | US | disclosed |