Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXM1 | Q08050 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840410 | 1.00 | FOXM1 (0.34) | FOXM1HRH3HTR2AGRM2CYP2C9 | |
| SCHEMBL8840423 | 0.92 | HRH3 (0.36) | HRH3CYP2C9CYP3A4KCNH2KDM1A | |
| SCHEMBL8840399 | 0.92 | HRH3 (0.35) | HRH3CYP2C9CYP3A4KCNH2CSF1R | |
| SCHEMBL8840454 | 0.90 | TP53 (0.34) | HRH3KDM1AMAOAMAOBMRGPRX4 | |
| SCHEMBL8840417 | 0.89 | GRM2 (0.34) | GRM2 | |
| SCHEMBL8840437 | 0.87 | KDM1A (0.31) | HRH3KDM1AMAOAMAOBMRGPRX4 | |
| SCHEMBL8840554 | 0.86 | MAPT (0.33) | CYP3A4KDM1AMAOAMAOBMRGPRX4 | |
| SCHEMBL8840395 | 0.84 | LRRK2 (0.31) | — | |
| SCHEMBL9035774 | 0.83 | KDM4E (0.35) | HRH3GRM2KDM1AMAOAMAOB | |
| SCHEMBL8840416 | 0.81 | TP53 (0.35) | HRH3CYP2C9CYP3A4KCNH2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |