Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840454 | 0.90 | TP53 (0.34) | KDM1AMAOAMAOBMRGPRX4HRH3 | |
| SCHEMBL8840417 | 0.89 | GRM2 (0.34) | — | |
| SCHEMBL8840423 | 0.88 | HRH3 (0.36) | KDM1AMAOAMAOBMRGPRX4HRH3 | |
| SCHEMBL8840554 | 0.88 | MAPT (0.33) | KDM1AMAOAMAOBMRGPRX4 | |
| SCHEMBL8840399 | 0.88 | HRH3 (0.35) | KDM1AMAOAMAOBMRGPRX4HRH3 | |
| SCHEMBL8840408 | 0.87 | FOXM1 (0.34) | KDM1AMAOAMAOBMRGPRX4HRH3 | |
| SCHEMBL8840410 | 0.87 | FOXM1 (0.34) | KDM1AMAOAMAOBMRGPRX4HRH3 | |
| SCHEMBL8840395 | 0.86 | LRRK2 (0.31) | — | |
| SCHEMBL9035774 | 0.83 | KDM4E (0.35) | KDM1AMAOAMAOBMRGPRX4HRH3 | |
| SCHEMBL8840416 | 0.79 | TP53 (0.35) | KDM1AMAOAMAOBMRGPRX4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |