Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8840545 | 0.84 | NPC1 (0.33) | BCHENPC1RAB9AALDH1A1PKM | |
| SCHEMBL8416182 | 0.78 | NPC1 (0.39) | MAPTBCHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8840390 | 0.76 | NPC1 (0.37) | BCHENPC1RAB9AMEN1KMT2A | |
| SCHEMBL8708906 | 0.76 | NPC1 (0.37) | BCHENPC1RAB9AMEN1KMT2A | |
| SCHEMBL8840614 | 0.71 | ALDH1A1 (0.39) | MAPTBCHENPC1RAB9AALDH1A1 | |
| SCHEMBL8415131 | 0.69 | HTR1A (0.37) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8840581 | 0.69 | HSD17B10 (0.39) | MAPTALDH1A1ATMMEN1KMT2A | |
| SCHEMBL8840398 | 0.67 | HTR1A (0.35) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8840547 | 0.66 | MEN1 (0.32) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8840514 | 0.66 | KLKB1 (0.34) | NPC1RAB9AALDH1A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |