Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 3/20 | 0.35 |
| ▸ | SI | P14410 | 3/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136881 | 0.77 | MAOA (0.42) | HSD17B10ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL11143431 | 0.70 | MAPT (0.39) | MAPTSMN1; SMN2ATMADRA2AADRA2B | |
| SCHEMBL8840614 | 0.69 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2HPGDTP53 | |
| SCHEMBL8840607 | 0.69 | MAPT (0.36) | ALDH1A1MAPTSMN1; SMN2HPGDTP53 | |
| SCHEMBL29682049 | 0.69 | ALDH1A1 (0.34) | HSD17B10ALDH1A1HTR2CTSHR | |
| SCHEMBL7104913 | 0.69 | ALDH1A1 (0.34) | HSD17B10ALDH1A1HTR2CTSHR | |
| SCHEMBL11755564 | 0.69 | ALDH1A1 (0.39) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL29340145 | 0.69 | HSD17B10 (0.52) | HSD17B10ALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL8373693 | 0.69 | ALDH1A1 (0.46) | HSD17B10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL900450 | 0.67 | MAOA (0.48) | HSD17B10ALDH1A1SMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650417-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0719255-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007890-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |