Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791049 | 0.85 | THRA (0.34) | THRATHRBS1PR4S1PR1S1PR3 | |
| SCHEMBL7091583 | 0.82 | RARB (0.47) | FAAHMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL7092568 | 0.81 | RARB (0.51) | THRATHRBS1PR1PTPN11MAPT | |
| SCHEMBL7791058 | 0.81 | FAAH (0.37) | THRATHRBPTPN11FAAHRARB | |
| SCHEMBL7091380 | 0.81 | RARB (0.44) | LMNAMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL7088460 | 0.78 | RARB (0.44) | FAAHMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL7092881 | 0.78 | THRA (0.41) | THRATHRBS1PR4S1PR1S1PR3 | |
| SCHEMBL8353800 | 0.78 | THRA (0.44) | THRATHRBS1PR4S1PR1S1PR3 | |
| SCHEMBL7793990 | 0.78 | AAK1 (0.35) | THRATHRBS1PR4S1PR1S1PR3 | |
| SCHEMBL9618022 | 0.78 | PTPN11 (0.44) | THRATHRBS1PR1PTPN11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9067350-A | — | — | None | — | — | JP | disclosed |
| JP-H0967350-A | ANTIFERRODIELECTRIC LIQUID CRYSTAL COMPOUND AND ANTIFERRODIELECTRIC LIQUID CRYSTAL COMPOSITION | TAKASAGO INTERNATL CORP | 1997-03-11 | — | — | JP | disclosed |