Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.47 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL27684505 | 0.90 | OR51E2 (0.50) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL28474712 | 0.87 | OR51E2 (0.60) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL10388600 | 0.82 | OR51E2 (0.54) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL27503412 | 0.81 | OR51E2 (0.68) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL3225022 | 0.80 | OR51E2 (0.75) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL27698786 | 0.80 | OR51E2 (0.75) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL5832885 | 0.80 | OR51E2 (0.75) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL17061486 | 0.80 | OR51E2 (0.75) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL28327039 | 0.79 | OR51E2 (0.65) | OR51E2CRBNFKBP5MEN1KMT2A | |
| 2-Pyrrolidone SCHEMBL4966601 | 0.78 | OR51E2 (0.71) | OR51E2CRBNFKBP5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100513394-C | Ketopyrrolidine sulfurate in liquid and its prpearing method | UNIV GUANGDONG TECHNOLOGY (CN) | 2009-07-15 | — | — | CN | disclosed |
| CN-101024625-A | Ketopyrrolidine sulfurate in liquid and its prpearing method | GUANGDONG POLYTECHNIQUE UNIV (CN) | 2007-08-29 | — | — | CN | disclosed |
| EP-0809103-A2 | Stable denaturants for use in electrophoretic techniques and methods of using the same | FMC CORPORATION (US) | 1997-11-26 | — | — | EP | disclosed |