Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824890 | 0.73 | GRIA4 (0.39) | HTTALDH1A1 | |
| SCHEMBL2804281 | 0.71 | TDP1 (0.41) | HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8842879 | 0.71 | MKNK1 (0.48) | HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL3869347 | 0.69 | KDM4E (0.41) | KDM4EALDH1A1HPGD | |
| SCHEMBL874572 | 0.69 | ALDH1A1 (0.41) | GPR35ALDH1A1HPGD | |
| Amflutizole SCHEMBL395613 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL16049222 | 0.65 | GPR35 (0.35) | GPR35 | |
| SCHEMBL4754963 | 0.65 | KDR (0.39) | HSD17B10HTTKDM4EALDH1A1HPGD | |
| SCHEMBL7817180 | 0.65 | GAA (0.34) | HTTALDH1A1 | |
| Hydrazine SCHEMBL9675518 | 0.64 | ALDH1A1 (0.52) | GPR35KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674887-A | Prevention of bone resorption | ELI LILLY AND COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5436258-A | Prevention of bone resorption | ELI LILLY AND COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0587378-A1 | Prevention of bone resorption | ELI LILLY AND COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |