Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326194 | 0.90 | PDCD1 (0.37) | PDCD1CD274NAMPTMEN1KMT2A | |
| SCHEMBL7330816 | 0.84 | MEN1 (0.33) | PDCD1CD274MEN1KMT2ATSHR | |
| SCHEMBL8842947 | 0.82 | UTS2R (0.34) | PDCD1CD274NAMPTMEN1KMT2A | |
| SCHEMBL7334319 | 0.82 | SIGMAR1 (0.37) | PDCD1CD274NAMPTMEN1KMT2A | |
| SCHEMBL7335699 | 0.82 | PDCD1 (0.38) | PDCD1CD274NAMPTUTS2RSIGMAR1 | |
| SCHEMBL7326692 | 0.82 | ADORA3 (0.36) | PDCD1CD274UTS2RDRD2 | |
| SCHEMBL7326616 | 0.82 | MEN1 (0.33) | MEN1KMT2ATP53MAPTGAA | |
| SCHEMBL7326950 | 0.82 | NPSR1 (0.37) | PDCD1CD274NAMPTMEN1KMT2A | |
| SCHEMBL7322514 | 0.81 | UTS2R (0.37) | PDCD1CD274NAMPTMEN1KMT2A | |
| SCHEMBL7326575 | 0.80 | MEN1 (0.31) | MEN1KMT2ATSHRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |