Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843104 | 0.92 | UTS2R (0.33) | UTS2RGAATPSAB1TPSD1TPSG1 | |
| SCHEMBL8842918 | 0.92 | UTS2R (0.35) | UTS2RGAAMAPTTPSAB1TPSD1 | |
| SCHEMBL7326194 | 0.86 | PDCD1 (0.37) | UTS2RGAAMAPTTPSAB1TPSD1 | |
| SCHEMBL7326692 | 0.85 | ADORA3 (0.36) | UTS2RTPSAB1TPSD1TPSG1PDCD1 | |
| SCHEMBL8842848 | 0.82 | PDCD1 (0.38) | UTS2RGAAMAPTPDCD1CD274 | |
| SCHEMBL8842925 | 0.81 | ITGB3 (0.38) | GAATPSAB1TPSD1TPSG1BRD4 | |
| SCHEMBL7325129 | 0.79 | ITGB3 (0.34) | UTS2RGAAMAPTMEN1KMT2A | |
| SCHEMBL7330816 | 0.78 | MEN1 (0.33) | GAAMAPTPDCD1CD274MEN1 | |
| SCHEMBL7334319 | 0.78 | SIGMAR1 (0.37) | UTS2RMAPTTPSAB1TPSD1TPSG1 | |
| SCHEMBL7335699 | 0.78 | PDCD1 (0.38) | UTS2RMAPTTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |