Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326612 | 0.89 | ITGB3 (0.38) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL7334965 | 0.86 | ITGB3 (0.38) | ITGB3ITGA2BHDAC1HDAC6MAPT | |
| SCHEMBL7327168 | 0.84 | SIGMAR1 (0.37) | ITGB3ITGA2BHDAC1HDAC6PDCD1 | |
| SCHEMBL7329988 | 0.82 | ADORA3 (0.36) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL7324001 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2BHDAC1HDAC6MAPT | |
| SCHEMBL7324841 | 0.79 | ITGB3 (0.44) | ITGB3ITGA2BMAPTALDH1A1 | |
| SCHEMBL7331886 | 0.79 | ITGB3 (0.33) | ITGB3ITGA2BHDAC1HDAC6MAPT | |
| SCHEMBL7334527 | 0.79 | ITGB3 (0.35) | ITGB3ITGA2B | |
| SCHEMBL7328359 | 0.79 | ITGB3 (0.43) | ITGB3ITGA2BMAPTPKMALDH1A1 | |
| SCHEMBL7321894 | 0.78 | ITGB3 (0.35) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |