Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 10/20 | 0.46 |
| ▸ | CTSA | P10619 | 2/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329795 | 0.92 | TACR3 (0.48) | CYP26A1CTSATACR3KMT2ATDP1 | |
| SCHEMBL7564581 | 0.92 | TACR3 (0.48) | CYP26A1CTSATACR3KMT2ATDP1 | |
| SCHEMBL8842886 | 0.89 | CASP1 (0.36) | KMT2A | |
| SCHEMBL8837019 | 0.81 | TACR3 (0.36) | TACR3KMT2AUTS2R | |
| SCHEMBL7333801 | 0.73 | GAA (0.39) | — | |
| SCHEMBL5926568 | 0.71 | CTSA (0.42) | CYP26A1CTSAKMT2AMMP12 | |
| SCHEMBL5425777 | 0.70 | CYP26A1 (0.52) | CYP26A1CTSATACR3KMT2ATDP1 | |
| SCHEMBL5926664 | 0.69 | CTSA (0.53) | CYP26A1CTSATACR3MMP12 | |
| SCHEMBL7335381 | 0.68 | ALDH1A1 (0.49) | CYP26A1TACR3KMT2A | |
| SCHEMBL7332776 | 0.67 | ALDH1A1 (0.44) | CYP26A1TACR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |