Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902570 | 0.79 | LTB4R (0.52) | LTB4RLTB4R2 | |
| SCHEMBL8561280 | 0.72 | LTB4R (0.51) | LTB4RLTB4R2 | |
| SCHEMBL8569951 | 0.72 | PTGER1 (0.39) | LTB4RLTB4R2BCHE | |
| SCHEMBL27300408 | 0.70 | LTB4R (0.54) | LTB4RLTB4R2FFAR4 | |
| SCHEMBL6899767 | 0.70 | NR1H4 (0.46) | LTB4RLTB4R2GSTP1 | |
| SCHEMBL8564257 | 0.70 | LTB4R (0.44) | LTB4RLTB4R2FFAR4 | |
| SCHEMBL6757535 | 0.69 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL6900710 | 0.69 | PIN1 (0.41) | LTB4RLTB4R2SMN1; SMN2GSTP1 | |
| SCHEMBL6899543 | 0.68 | LTB4R (0.40) | LTB4RLTB4R2SMN1; SMN2GSTP1 | |
| SCHEMBL6756183 | 0.67 | LTB4R (0.48) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777472-A2 | METHODS FOR IDENTIFYING AND TREATING RESISTANT TUMORS | ELI LILLY AND COMPANY (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006604-A2 | METHODS FOR IDENTIFYING AND TREATING RESISTANT TUMORS | ELI LILLY AND COMPANY (US) | 1996-03-07 | — | — | WO | disclosed |