Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433410 | 0.85 | FOLH1 (0.42) | MMP2MMP9TLR2CA1CA2 | |
| SCHEMBL27799398 | 0.85 | FOLH1 (0.42) | MMP2MMP9TLR2CA1CA2 | |
| SCHEMBL232126 | 0.85 | FOLH1 (0.42) | MMP2MMP9TLR2CA1CA2 | |
| Hydrochloric Acid SCHEMBL15923983 | 0.83 | FOLH1 (0.41) | MMP2MMP9TLR2CA1CA2 | |
| SCHEMBL45766 | 0.80 | FOLH1 (0.49) | MMP2MMP9TLR2CA1CA2 | |
| SCHEMBL6676701 | 0.80 | FOLH1 (0.49) | MMP2MMP9TLR2CA1CA2 | |
| Hydrochloric Acid SCHEMBL15923088 | 0.79 | FOLH1 (0.47) | MMP2MMP9TLR2CA1CA2 | |
| Acetic Acid SCHEMBL268741 | 0.76 | FOLH1 (0.45) | MMP2MMP9TLR2CA1CA2 | |
| SCHEMBL27453149 | 0.75 | TLR2 (0.61) | MMP2MMP9TLR2NQO1GGT1 | |
| SCHEMBL18668641 | 0.72 | MMP2 (0.49) | MMP2MMP9TLR2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597809-A | METHYL ASPARTATE MEDIATED RETINAL CELL DAMAGE | MASSACHUSETTS EYE & EAR INFIRMARY (US) | 1997-01-28 | — | — | US | disclosed |