Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.39 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.39 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843360 | 1.00 | TSHR (0.43) | TSHRPTP4A3PTP4A1PTP4A2CYP2C9 | |
| SCHEMBL7889591 | 0.81 | TSHR (0.49) | TSHRZDHHC20ZDHHC2SMN1; SMN2CYP3A4 | |
| SCHEMBL541316 | 0.73 | PTP4A1 (0.46) | TSHRPTP4A3PTP4A1PTP4A2CYP2C9 | |
| SCHEMBL7545551 | 0.71 | ALOX15 (0.41) | SMN1; SMN2LMNAPOLBKDM4EHPGD | |
| SCHEMBL6293723 | 0.71 | PTP4A1 (0.49) | TSHRPTP4A3PTP4A1PTP4A2CYP2C9 | |
| SCHEMBL8760455 | 0.71 | TSHR (0.50) | TSHRZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL4088999 | 0.71 | CYP2C9 (0.45) | TSHRPTP4A3PTP4A1PTP4A2CYP2C9 | |
| SCHEMBL1566521 | 0.71 | CYP2C9 (0.45) | TSHRPTP4A3PTP4A1PTP4A2CYP2C9 | |
| SCHEMBL1566520 | 0.71 | CYP2C9 (0.45) | TSHRPTP4A3PTP4A1PTP4A2CYP2C9 | |
| SCHEMBL7117459 | 0.70 | PTP4A3 (0.48) | TSHRPTP4A3PTP4A1PTP4A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624981-A | Polyalkylpiperidine containing acetic acid and 3-amino-acrylic acid derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |
| US-5610210-A | Aminovinylphosphonic ester stabilizers for organic material | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |