Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH1C | P00326 | 2/20 | 0.39 |
| ▸ | ADH1A | P07327 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5055068 | 0.83 | CYP2D6 (0.61) | ALDH1A1CYP2D6SMN1; SMN2EPHX1ADH1B | |
| SCHEMBL8843355 | 0.81 | TSHR (0.43) | TSHRALDH1A1CYP2D6SMN1; SMN2ZDHHC20 | |
| SCHEMBL8843360 | 0.81 | TSHR (0.43) | TSHRALDH1A1CYP2D6SMN1; SMN2ZDHHC20 | |
| SCHEMBL8760455 | 0.76 | TSHR (0.50) | TSHRZDHHC20ZDHHC2EPHX1FAAH | |
| SCHEMBL18741294 | 0.74 | TSHR (0.60) | TSHRALDH1A1SMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL29940 | 0.73 | ACHE (0.56) | TSHRZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL6449183 | 0.73 | TSHR (0.58) | TSHRALDH1A1EPHX1HPGDFAAH | |
| SCHEMBL5366068 | 0.73 | TSHR (0.46) | TSHRZDHHC20ZDHHC2EPHX1FAAH | |
| SCHEMBL6332081 | 0.72 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1 | |
| SCHEMBL8769221 | 0.72 | EPHX1 (0.59) | TSHRZDHHC20ZDHHC2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172232-B1 | Light stabilizers based on sterically hindered amines | CLARIANT GMBH (DE) | 2001-01-09 | — | — | US | disclosed |