Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418820 | 0.89 | LMNA (0.51) | LMNAALDH1A1NPC1RAB9AGAA | |
| SCHEMBL5801663 | 0.81 | KMT2A (0.65) | LMNAALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9697869 | 0.81 | ESRRG (0.56) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7392747 | 0.80 | ACACB (0.48) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8340802 | 0.79 | SMN1; SMN2 (0.50) | LMNAALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8338354 | 0.78 | MEN1 (0.55) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8338756 | 0.78 | LMNA (0.49) | LMNAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL27959104 | 0.78 | PTPN1 (0.47) | LMNAALDH1A1NPC1RAB9AGAA | |
| SCHEMBL6447258 | 0.78 | HDAC1 (0.52) | LMNAALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9937386 | 0.75 | SMN1; SMN2 (0.47) | LMNAALDH1A1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |