Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697869 | 0.84 | ESRRG (0.56) | HPGDKMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL8340802 | 0.82 | SMN1; SMN2 (0.50) | LMNAHPGDKMT2AALDH1A1KDM4E | |
| SCHEMBL1240060 | 0.82 | ALDH1A1 (0.51) | LMNAHPGDKMT2AALDH1A1HTT | |
| SCHEMBL21776624 | 0.81 | LMNA (0.49) | LMNAHPGDKMT2AALDH1A1HTT | |
| SCHEMBL8338354 | 0.81 | MEN1 (0.55) | HPGDKMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL2530016 | 0.80 | KMT2A (0.63) | LMNAHPGDKMT2AALDH1A1HTT | |
| SCHEMBL4418820 | 0.80 | LMNA (0.51) | LMNAALDH1A1KDM4ERAB9AL3MBTL1 | |
| SCHEMBL8843451 | 0.78 | LMNA (0.51) | LMNAKMT2AALDH1A1HTTRAB9A | |
| SCHEMBL7434290 | 0.78 | KCNQ3 (0.53) | LMNAHPGDKMT2AALDH1A1KDM4E | |
| SCHEMBL1668799 | 0.76 | GAA (0.50) | LMNAHPGDKMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |