SCHEMBL8340802

SCHEMBL8340802

CC(=O)NNCc1ccc(C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 5/20 0.49
KMT2A Q03164 8/20 0.47
MEN1 O00255 6/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP1 P29466 1/20 0.47
BLM P54132 1/20 0.47
PLEC Q15149 1/20 0.47
HSD17B10 Q99714 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4123487 0.86 SMN1; SMN2 (0.56) SMN1; SMN2NPC1KMT2AMEN1ALDH1A1
SCHEMBL9697869 0.86 ESRRG (0.56) NPC1KMT2AMEN1ALDH1A1HPGD
SCHEMBL10682559 0.82 SMN1; SMN2 (0.49) SMN1; SMN2NPC1KMT2AMEN1ALDH1A1
SCHEMBL8338354 0.82 MEN1 (0.55) SMN1; SMN2NPC1KMT2AMEN1ALDH1A1
SCHEMBL8338756 0.82 LMNA (0.49) NPC1KMT2AALDH1A1HPGDKDM4E
SCHEMBL4418820 0.82 LMNA (0.51) SMN1; SMN2NPC1ALDH1A1KDM4EGAA
Hydrochloric Acid SCHEMBL3467437 0.81 SMN1; SMN2 (0.47) SMN1; SMN2NPC1KMT2AMEN1ALDH1A1
SCHEMBL8843451 0.79 LMNA (0.51) SMN1; SMN2NPC1KMT2AMEN1ALDH1A1
SCHEMBL171709 0.79 KMT2A (0.66) SMN1; SMN2NPC1KMT2AMEN1ALDH1A1
SCHEMBL22745866 0.78 MMP13 (0.50) ALDH1A1HPGDKDM4EPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299518-B1 FIBRE PAPER COMPRISING POD AND PREPARATION METHOD THEREFOR JIANGSU ZANPOD NEW MAT CO LTD (CN) 2020-12-02 EP disclosed
US-5948780-A ADMINISTERING A METALLOPROTEINASE INHIBITOR WARNER-LAMBERT COMPANY (US) 1999-09-07 US disclosed
US-5672615-A MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS NOVARTIS CORPORATION (US) 1997-09-30 US disclosed