Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337943 | 0.85 | HTT (0.52) | KMT2AALDH1A1RAB9AGAAUSP2 | |
| SCHEMBL8843510 | 0.75 | HTR1A (0.40) | DPP4KMT2AGAA | |
| SCHEMBL8843614 | 0.74 | HTT (0.54) | KMT2AALDH1A1RAB9AGAAUSP2 | |
| Hydrochloric Acid SCHEMBL8843297 | 0.73 | HTT (0.53) | KMT2AALDH1A1RAB9AUSP2HTT | |
| SCHEMBL28071516 | 0.69 | HSD17B10 (0.45) | DPP4ALDH1A1KDM4E | |
| SCHEMBL6803339 | 0.68 | TLR2 (0.54) | — | |
| SCHEMBL28071555 | 0.68 | MMP1 (0.54) | DPP4KMT2AALDH1A1DPP7 | |
| Hydrochloric Acid SCHEMBL28071361 | 0.68 | KDM4E (0.45) | DPP4KMT2AALDH1A1KDM4E | |
| SCHEMBL27350497 | 0.68 | TLR2 (0.54) | — | |
| SCHEMBL8065316 | 0.68 | ALDH1A1 (0.64) | KMT2AALDH1A1RAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |